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2026AI for Science · Generative Models

Diffusion Guided Particle Sampling for Bayesian Inverse PDE Problems

Ongoing

Nicholas Bai

Ongoing — AI + Science Lab, Caltech

Advised by Jiachen Yao, Xi Deng, Anima Anandkumar

Leveraging diffusion priors to recover the full posterior for inverse PDE problems, instead of a single MAP estimate.

Many scientific inverse problems are ill-posed: several different parameter fields all explain the same observations. Standard maximum-a-posteriori approaches return a single solution and disregard the distributional perspective entirely.

This project designs diffusion-prior, particle-based samplers for Bayesian inverse PDE problems, with the goal of recovering the full multimodal posterior. The diffusion model supplies a learned prior over plausible fields; the particle method carries the multimodality through inference.

This is ongoing work in Prof. Anima Anandkumar's AI + Science Lab at Caltech, supported by a Carl F. Braun SURF Fellowship.